Ibuprofen 200mg
Faster onset, ideal for acute pain.
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220mg tablets, 100-count bottle
Order FDA-Approved Naproxen 220mg — Fewer Doses, Longer Relief for Arthritis & Pain
220mg sodium tablets, 80-count bottle
Naproxen Sodium 220mg is an OTC nonsteroidal anti-inflammatory drug (NSAID) best known by the brand name Aleve. Unlike ibuprofen which requires dosing every 4–6 hours, naproxen offers extended 8–12 hour relief with just one tablet — making it ideal for conditions like arthritis, tendinitis, and chronic back pain where sustained relief throughout the day is essential.
Naproxen 220mg is indicated for the relief of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, tendinitis, bursitis, gout flares, muscle aches and back pain, menstrual cramps, headache and migraine, fever reduction, and minor acute injuries. It is approved for OTC use and does not require a prescription for standard adult doses.
Like other NSAIDs, naproxen inhibits COX-1 and COX-2 enzymes to block prostaglandin production, reducing pain, fever, and inflammation. Its longer half-life compared to ibuprofen means the drug stays active in your system for 8–12 hours per dose. Onset of action typically occurs within 30–60 minutes, with peak pain relief at 1–2 hours.
Adults and children 12 and over: Take 1 tablet (220mg) every 8 to 12 hours. If needed, a second tablet may be taken within the first hour. Do not exceed 2 tablets (440mg) in any 8–12 hour period or 3 tablets (660mg) in 24 hours. Take with food or milk to reduce stomach upset. Do not use for more than 10 days for pain or 3 days for fever without medical direction.
Suitable for adults and children 12+ for short-term OTC use. Avoid if you have stomach ulcers, kidney disease, heart disease, or take blood thinners. Elderly patients should use with caution due to increased GI risk. Not for use in late pregnancy. Always consult your doctor for chronic pain management.
Common side effects include stomach upset, nausea, heartburn, and headache. Less common: dizziness, ringing in ears. Serious risks (rare with short-term OTC use): GI bleeding, kidney issues, cardiovascular effects. Take with food or antacids to reduce stomach irritation. Not recommended for long-term use without medical supervision.
Promedic is a licensed US online pharmacy committed to providing FDA-approved OTC medications at competitive prices. We source all products from reputable US-licensed distributors and manufacturers. Every order is handled with discretion, packaged securely, and shipped to all 50 states. Our pharmacy team is available to answer any questions about Naproxen 220mg or any other products in our inventory. Order with confidence — quality and customer service are our top priorities.
Do I need a prescription to buy Naproxen 220mg?
No. Naproxen 220mg is an over-the-counter (OTC) medication available without a prescription for standard adult use.
How quickly will my order arrive?
We offer standard and expedited shipping to all 50 US states. Contact us for estimated delivery times to your location.
Is the generic version as effective as the brand name?
Yes. All OTC medications we carry must meet FDA quality and efficacy standards. Generic versions contain the same active ingredient at the same strength as their branded equivalents.
Naproxen provides 8–12 hours of relief per dose — significantly longer than Ibuprofen (4–6 hours) or acetaminophen. This makes it ideal for chronic pain conditions like arthritis where consistent coverage is needed. Source: MedlinePlus: Naproxen.
Naproxen and Ibuprofen are both NSAIDs with similar effectiveness, but naproxen has a longer duration. Naproxen 220mg OTC is equivalent in strength to about 200–400mg of ibuprofen. For quick short-term relief, ibuprofen may act faster; for all-day coverage, naproxen is preferred.
For short-term use (under 10 days for pain, 3 days for fever), daily naproxen is generally safe for healthy adults. Long-term daily use increases risk of stomach ulcers, cardiovascular events, and kidney issues. Always consult a healthcare provider for chronic use. See FDA NSAID Safety Warning.
Naproxen is not recommended if you have kidney disease, stomach ulcers, heart disease, or take blood thinners. Do not use in the third trimester of pregnancy. Not suitable for children under 12 without medical advice.
Aleve is the brand name; naproxen sodium 220mg is the generic active ingredient. Generic naproxen 220mg is bioequivalent to Aleve and provides the same 8–12 hour relief at a lower cost.
Promedic is a US licensed pharmacy delivering genuine FDA-approved OTC medications to all 50 states. Secure ordering, discreet packaging, and competitive pricing.
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Healthcare Professional & Medical Reviewer, Promedic
Andrew Gaon is a healthcare professional and medical reviewer at Promedic, where he helps ensure that medical content is accurate, evidence-based, and easy for patients to understand. He reviews articles for clinical accuracy, current treatment guidelines, and patient safety, ensuring information meets high editorial and healthcare standards. Andrew is dedicated to providing reliable, trustworthy medical information that empowers patients to make informed healthcare decisions.