Viagra (Sildenafil)
Original ED medication, 4-6 hours duration.
Est: $8-15 View Details
Order the 36-Hour ED Pill — FDA-Approved, Discreet USA Delivery
Cialis is a prescription medication containing Tadalafil, used to treat erectile dysfunction (ED) in men. Developed by Eli Lilly and FDA-approved in 2003, Cialis has become one of the most popular ED medications in America due to its unique long-lasting effect of up to 36 hours - earning it the nickname "the weekend pill."
Unlike other ED medications that last 4-6 hours, Cialis's extended duration provides unprecedented flexibility and spontaneity, allowing men to engage in sexual activity within a much wider time window after taking the medication.
Tadalafil, the active ingredient in Cialis, is a phosphodiesterase type 5 (PDE5) inhibitor. It works by:
Cialis is FDA-approved for men over 18 experiencing erectile dysfunction. However, medical consultation is essential. Cialis may not be suitable if you:
On-Demand Dosing:
Daily Dosing:
Studies demonstrate Cialis's high effectiveness:
Common side effects (affecting 1-10% of users):
Rare but Serious:
Never Combine With:
Use Caution With:
Q: How long does Cialis take to work?
A: Cialis typically works within 30-60 minutes. Effects can last up to 36 hours.
Q: Can I take Cialis every day?
A: Yes, low-dose Cialis (2.5mg or 5mg) is FDA-approved for daily use, providing continuous readiness.
Q: Does Cialis work better than Viagra?
A: Both are effective. Cialis lasts longer (36 hours vs 4-6 hours) but "better" depends on individual needs and preferences.
Q: Can I drink alcohol with Cialis?
A: Moderate alcohol (1-2 drinks) is generally okay. Excessive alcohol may reduce effectiveness and increase side effects.
Q: Is generic Tadalafil as good as brand Cialis?
A: Yes, generic Tadalafil contains the same active ingredient and is FDA-approved as bioequivalent to brand Cialis.
Cialis lasts up to 36 hours — earning its nickname the "weekend pill." This means you can take one dose on a Friday evening and remain ready for intimacy through Sunday. Peak effects occur around 2 hours after taking it.
Cialis Daily (2.5mg or 5mg): Taken once every day, maintaining a constant level in your bloodstream for spontaneous readiness anytime. On-demand Cialis (10mg or 20mg): Taken 30–45 minutes before sexual activity. See our guide: Cialis Daily vs On-Demand
The main difference is duration: Cialis lasts up to 36 hours while Viagra lasts 4–6 hours. Cialis is also less affected by food. Both have comparable effectiveness rates (around 80%). Full comparison: Cialis vs Viagra
Yes. Unlike Viagra, Cialis can be taken with or without food — including a high-fat meal — without significantly affecting its absorption or effectiveness. This flexibility is one of Cialis's most valued features.
Yes, when ordering from a US licensed pharmacy like Promedic. All Cialis on proomedic.com is FDA-approved Tadalafil from licensed manufacturers, shipped in discreet plain packaging to all 50 US states. Read: How to Buy ED Medication Online Safely
For on-demand use: start with 10mg, adjustable to 20mg if needed. For daily use: 2.5mg or 5mg once per day at the same time. Do not exceed 20mg in 24 hours. Consult your doctor for personalized dosing.
Promedic is a US licensed online pharmacy. All ED medications are FDA-approved, sourced from licensed manufacturers, and shipped in plain discreet packaging to all 50 states.
Order Now — Go to Checkout
Healthcare Professional & Medical Reviewer, Promedic
Andrew Gaon is a healthcare professional and medical reviewer at Promedic, where he helps ensure that medical content is accurate, evidence-based, and easy for patients to understand. He reviews articles for clinical accuracy, current treatment guidelines, and patient safety, ensuring information meets high editorial and healthcare standards. Andrew is dedicated to providing reliable, trustworthy medical information that empowers patients to make informed healthcare decisions.